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In Vitro Lungs Model

This two days hands-on training hosted by Epithelix will cover practical use of respiratory in vitro 3D tissues and exposure devices to evaluate acute and repeated dose inhalation toxicity. To mimic systemic context, interconnection strategies of lung tissues will be presented.

The training will only take place if minimum of 8 participants is reached.

Registration fee includes the participant booklet, catering and social dinner.

The training will start with 0.5 day lectures and will be followed by 1.5 days of practical training (Hands on-training) where participants, divided in small groups will get the chance to manipulate and see the critical steps of the methods with the experts. This is a perfect way to quickly approach a method, as well as data analysis and interpretation.

Registration fee includes the participant booklet, catering and social dinner.

Acute and chronic cardiotoxicity

The course is a two-day laboratory workshop in Leiden. This training instructs the attendee in best practices procedures for in silico and in vitro assays related to acute and chronic cardiotoxicity.

Participants will learn among other things:

  • Regulatory context to apply these methodologies as well as strengths, weaknesses and future prospects (UCB – Dr Delaunois)
  • Cell handling of human iPSC-derived cardiomyocytes (e.g. thawing procedure, cells seeding) (NCardia)
  • Preparation of cryopreserved hiPSC-derived cardiomyocytes in 48/96 or 348 well plates (NCardia)
  • Exposure of cells with cardiotoxic compounds using different readouts such as CiPA-like MEA (Micro-electrode array) and calcium flux assay (NCardia)
  • Risk Assessment, validation, analysis interpretation and decision making using hiPS-cells for early drug discovery and development (Jannsen Pharma – Dr. Kreir)
  • In silico assessment of the effects of various compounds in MEA/hiPSC-CM assays: modelling and numerical simulations (inria)

The training will start with half day lectures and will be followed by 1.5 days of practical training (Hands on-training) where participants, divided in small group will get the chance to manipulate and see the critical steps of the methods with the experts. This is a perfect way to quickly approach a method, as well as data analysis and interpretation.

Draft Agenda will be soon available.

The training will only take place if a minimum of 4 participants is reached.

Registration fee includes the participant booklet, catering and social dinner.

Irritation oculaire in vitro

  • Fee-based
  • 21 novembre 2019
  • Lyon, France
    • Lors de cette formation, le contexte général de l’évaluation toxicologique sera abordé ainsi  que le statut   actuel   de   la   validation   des   méthodes alternatives en Europe (Règlement   CE   1223/2009, SCCS)   ainsi   que   les   recommandations   internationales (OECD Test Guidelines, ICCR).
    • Après   introduction   des   tests   et   méthodes  in vitro validés   pour   les   cosmétiques,   les avantages  et   les   limites   de   chaque méthode d’essai   seront appréhendées   par   des   cas  concrets.   Les   participants   auront   l’opportunité   de   traiter des données et de les interpréter.  Des méthodes non réglementaires seront également abordées (irritation oculaire faible). 

    La formation aura lieu s’il y a au moins 5 participants inscrits.

Skin and Eye Irritation

  • Fee-based
  • 3-4 december 2019
  • Brussels, Belgium

Irritation oculaire in vitro

  • Fee-based
  • 19 Mars 2020
  • Lyon, France
  • Lors de cette formation, le contexte général de l’évaluation toxicologique sera abordé ainsi  que le statut   actuel   de   la   validation   des   méthodes alternatives en Europe (Règlement   CE   1223/2009, SCCS)   ainsi   que   les   recommandations   internationales (OECD Test Guidelines, ICCR).
  • Après   introduction   des   tests   et   méthodes  in vitro validés   pour   les   cosmétiques,   les avantages  et   les   limites   de   chaque méthode d’essai   seront appréhendées   par   des   cas  concrets.   Les   participants   auront   l’opportunité   de   traiter des données et de les interpréter.  Des méthodes non réglementaires seront également abordées (irritation oculaire faible). 

La formation aura lieu s’il y a au moins 5 participants inscrits.

contact us for more info

+32 (0)485 52 39 45